Physiolution is an innovative company focused on bio-predictive testing of oral medicines. Physiolution was launched in 2009 to commercialize tools simulating the mechanics of the human GI tract. The company is a privately owned and self-funded LLC.
The cutting-edge test methods utilized by Physiolution were established by the founders and co-workers and are based on long experience in the fields of physiology, bio-predictive dissolution testing, as well as the use of numerical methods in pharmacokinetics and pharmacodynamics. The unique test methods and computational simulations developed by the Physiolution Team enable solving essential problems arising during the development and clinical evaluation of oral medicines.
The test devices and computational methods used by Physiolution realistically simulate the mechanistic and physicochemical conditions of the gastrointestinal transit and thus enable a realistic assessment of safety and biopharmaceutical reliability of formulations in the development stage. The applicability of the test devices and procedures was successfully verified in numerous clinical examples as well as in routine testing of oral medicines.
To be the trusted partner in medicine development, inventing technologies that realistically simulate GI tract and advance the future of oral drug delivery.
Translating GI complexity into a set of reliable, biopredictive tests.
To turn formulation uncertainty into predictable outcomes.
Preclinical characterization of oral medicines:
