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AMP

™

The Advanced Modular Platform (AMP™ ) is the first tool that combines an adequate and customized simulation of in-vivo conditions.

The AMP™ consists of a universal device and interchangeable modules for specific tests. It realistically simulates the dynamics of the mechanical and
physicochemical conditions of the GI transit, allows the use of bio-relevant liquids and dynamic fluctuations of the physicochemical conditions, simulates
the bio-relevant temperature gradients and is suitable for bio-predictive and compendial dissolution testing.

AMP

™

The basic functions of the AMP™ are:

  • stress test with simulation of the GI motility forces of physiological intensity
  • dissolution testing combined with dynamic pH control unit (integrated pHysio-grad® ) and dynamic adjustment of the pH by gasses (CO2 , N2 , compressed air) and/or liquids (NaOH, NaHCO3 , Na2CO3 , HCl)
  • simulation of the dynamic digestion and processing of the dissolution media
  • a transfer model combined with each of configurations specified above
  • standard dissolution testing in the USP Apparatus 2, including mini-vessels

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